1. Presence of pyrroloquinazoline alkaloid in Adhatoda vasica attenuates inflammatory response through the downregulation of pro-inflammatory mediators in LPS stimulated RAW 264.7 macrophages

Reddy Amala, Sundaresan Sujatha*

BioImpacts. 2021;11(1): 15-22. doi: 10.34172/bi.2021.03

PMCID: PMC7803918 PMID: 33469504 Scopus ID: 85099218046

Article

PDF

Full Text

XML

Cited By:

LPS stimulated the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 by binding toTLR-4. iNOS produced enormous nitric oxide (NO) that stimulated COX-2 activity and prostaglandin E2 which further induced the production of pro-inflammatory cytokines leading to inflammation. ALK-F of A. vasica could attenuate iNOS and COX-2 gene expression reducing NO production.

Original Article

2. Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study

Zahra Bahadoran , Parvin Mirmiran, Fereidoun Azizi, Asghar Ghasemi*

Bioimpacts. 2024;14(5): 29917. doi: 10.34172/bi.2024.29917

PMCID: PMC11406430 PMID: 39296799 Scopus ID: 85209255799

Article

PDF

Suppl 1

Full Text

XML

Cited By:

Submit Your Paper Instructions for Authors Aims and Scope Editorial Board Editorial Policies Publication Ethics Policies Editorial Board Policy Abstracting and Indexing Archive

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences.
Acceptance rate (2024): 20%
Publication fee: Free of charge

Indexing/Abstracting Info
PubMed; PubMed Central; Scopus; Science Citation Index Expanded; Google Scholar; SJR; Essential Science Indicators; Embase; EBSCOhost; CAS: DOAJ: SHERPA/RoMEO
Member of
Follower of ICMJE
Permission: Creative Commons